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Selected Publications

Peptide self-assembly as a strategy for facile immobilization of redox enzymes on carbon electrodes
Tzachi Grinberg, Oren Ben Zvi,  Lihi Adler-Abramovich* and Iftach Yacoby*

Carbon Energy: e411 (2023) 

A PSII photosynthetic control is activated in anoxic cultures of green algae following illumination
Yuval Milrad, Valéria Nagy, Tamar Elman, Maria Fadeeva, Szilvia Z. Tóth and Iftach Yacoby 

Communications Biology volume 6, Article number: 514 (2023) 

A two-phase protocol for ambient hydrogen production using Chlamydomonas reinhardtii
Tamar Elman and Iftach Yacoby 

STAR protocols, (2022):3:101640

Advances and challenges in photosynthetic hydrogen production 
Kevin E. Redding, Jens Appel, Marko Boehm, Marc M. Nowaczyk, Iftach Yacoby and Kirstin Gutekuns

Published on May 2022

Trends in Biotechnology

Tamar Elman,  Thi Thu Hoai Ho, Yuval Milrad, Michael Hippler and Iftach Yacoby 

Cell Reports Physical Science, (2022): 3(4): 100828

Photosystem I light-harvesting proteins regulate photosynthetic electron transfer and hydrogen production.   
Thi Thu Hoai Ho, Chris Schwier, Tamar Elman, Vera Fleuter, Karen Zinzius, Martin Scholz, Iftach YacobyFelix E Buchert, Michael Hippler *

Published on Dec 2021

Plant Physiology

*Corresponding author

Use of plant chloroplast RNA-binding proteins as orthogonal activators of chloroplast transgenes in the green alga Chlamydomonas reinhardtii
Noam Shahar, Tamar Elman, Rosalind Williams-Carrier, Oren Ben-Zvi, Iftach Yacoby *,
Alice Barkan*

Published on Oct 2021

Algal Reaserch

*Corresponding authors

Phylloquinone is the principal Mehler reaction site within photosystem I in high light
Marina Kozuleva, Anastasia Petrova, Yuval Milrad, Alexey Semenov, Boris Ivanov, Kevin E Redding, Iftach Yacoby *

Published on May 2021

Plant Physiology

*Corresponding author

Protection of Oxygen-Sensitive Enzymes by Peptide Hydrogel
Oren Ben-Zvi, Itzhak Grinberg, Asuka A Orr, Dror Noy, Phanourios Tamamis, Iftach Yacoby*, Lihi Adler-Abramovich*

Published on April 2021

ACS Nano

*Corresponding authors  

Bi-directional electron transfer between H2 and NADPH mitigates light fluctuation responses in green algae
Yuval Milrad, Shira Schweitzer, Yael Feldman, Iftach Yacoby*

Published on February 2021

Plant Plant Physiology

*Corresponding author  

Engineered clostridial [FeFe]-hydrogenase shows improved O2 tolerance in Chlamydomonas reinhardtii
Tamar Elman, Shira Schweitzer,  Noam Shahar, James Schwartz and Iftach Yacoby* 

Published on Aug 2020

International Journal of Hydrogen Energy

*Corresponding author  

Rewiring photosynthesis: a Photosystem I-hydrogenase chimera that makes H2 in vivo
Andrey Kanygin,   Yuval Milrad,   Chandrasekhar Thummala,   Kiera T. Reifschneider,   Patricia Baker,   Pini Marcu,   Iftach Yacoby*  and  Kevin E Redding*
Published on Apr 2020
Energy and Environmental Science
*Corresponding authors  

The Integration of Multiple Nuclear- Encoded Transgenes in the Green Alga Chlamydomonas reinhardtii Results in Higher Transcription Levels
Noam Shahar, Shira Landman, Iddo Weiner, Tamar Elman, Eyal Dafni, Yael Feldman, Tamir Tuller* and Iftach Yacoby*
Published on Feb 2020
Frontiers in Plant Sciences
*Corresponding authors  


CSO – A sequence optimization software for engineering chloroplast expression in Chlamydomonas reinhardtii

Iddo Weiner, Yael Feldman, Noam Shahar, Iftach Yacoby* and Tamir Tuller*

Published on Dec 2019

Algal Research

*Corresponding authors  


Re-routing photosynthetic energy for continuous hydrogen production in vivo
Oren Ben-Zvi, Eyal Dafni, Yael Feldman, and Iftach Yacoby*
Published on November 2019
Biotechnology for Biofuels
*Corresponding author


Solving the riddle of the evolution of Shine-Dalgarno based translation in chloroplasts
Iddo Weiner, Noam Shahar, Pini Marco, Iftach Yacoby* and Tamir Tuller*
Published on September 2019
Molecular Biology and Evolution
*Corresponding authors  


Binding of ferredoxin NADP+ oxidoreductase (FNR) to plant photosystem I
Pini Marco, Tamar Elman, and Iftach Yacoby*

Published on July 2019

Biochimica et Biophysica Acta


Paradigm Shift in Algal H2 Production: Bypassing Competitive Processes
Szilvia Z.Tóth* and Iftach Yacoby*
Published on June 2019
Trends in Biotechnology
*Corresponding authors  


Prediction and large-scale analysis of primary operons in plastids reveals unique genetic features in the evolution of chloroplasts
Noam Shahar, Iddo Weiner, Lior Stotsky, Tamir Tuller*, Iftach Yacoby*
Published on March 2019
Nucleic Acids Research
*Correspondence authors
ChimeraUGEM: unsupervised gene expression modeling in any given organism
Alon Diament, Iddo Weiner, Noam Shahar, Shira Landman, Yael Feldman, Shimshi Atar, Meital Avitan, Shira Schweitzer, Iftach Yacoby*, Tamir Tuller*
Published on February 2019
*Correspondence authors
Image processing software for high throughput quantification of colony luminescence
Eyal Dafni, Iddo Weiner, Noam Shahar, Tamir Tuller*, Iftach Yacoby*
Published on January 2019
*Correspondence authors

Overcoming the expression barrier of the ferredoxin‑hydrogenase chimera in Chlamydomonas reinhardtii supports a linear increment in photosynthetic hydrogen output
Iddo Weiner, Noam Shahar, Yael Feldman, Shira Landman, Yuval Milrad, Oren Ben-Zvi, Meital Avitan, Eyal Dafni, Shira Schweitzer, Haviva Eilenberg, Shimshi Atar, Alon Diament, Tamir Tuller*, Iftach Yacoby*
Published on July 2018
Algal Research
*Correspondence authors

Green algal hydrogenase activity is outcompeted by carbon fixation before inactivation by oxygen takes place
Yuval Milrad, Shira Schweitzer, Yael Feldman, Iftach Yacoby*
Published on May 2018
Plant Physiology
*Correspondence author

Binding of ferredoxin to algal photosystem I involves a single binding site and is composed of two thermodynamically distinct events
Pini Marco, Marina Kozuleva, Haviva Eilenberg, Yuval Mazor, Peter Gimeson, Andrey Kanygin, Kevin Redding, Iddo Weiner and Iftach Yacoby*
Published on April 2018
Biochimica et Biophysica Acta
*Correspondence author

Enhancing Heterologous Expression in Chlamydomonas reinhardtii by Transcript Sequence Optimization
Iddo Weiner, Shimshi Atar, Shira Schweitzer, Haviva Eilenberg, Yael Feldman, Meital Avitan, Mor Blau, Avihai Danon, Tamir Tuller*, and Iftach Yacoby*
Published on April 2018
The Plant Journal
*Correspondence authors
A myovirus encoding both photosystem I and II proteins enhances cyclic electron flow in infected Prochlorococcus cells
​Svetlana Fridman, José Flores-Uribe, Shirley Larom, Onit Alalouf, Oded Liran, Iftach Yacoby, Faris Salama, Benjamin Bailleul, Fabrice Rappaport, Tamar Ziv, Itai Sharon, Francisco M. Cornejo-Castillo, Alon Philosof, Christopher L. Dupont, Pablo Sánchez, Silvia G. Acinas, Forest L. Rohwer, Debbie Lindell & Oded Béjà
Published on October 2017
Nature Microbiology 
The dual effect of a ferredoxin-hydrogenase fusion protein in vivo: successful divergence of the photosynthetic electron flux towards hydrogen production and elevated oxygen tolerance
Eilenberg H, Weiner I, Ben-Zvi O, Pundak C, Marmari A, Liran O, Wecker SM Milrad Y, and Yacoby I*
Published on August 2016
Biotechnology for Biofuels
*Correspondence author

Microoxic niches within the thylakoid stroma of air-grown C. reinhardtii protect [FeFe]-hydrogenase
Liran O, Semyatich R, Milrad Y, Eilenberg H, weiner I and Yacoby I*
Published on September 2016
Plant Physiology
*Correspondence author
The In-vitro enhancement of FeFe Hydrogenase activity By Superoxide Dismutase
Ben-Zvi O and Yacoby I* 

Published on October 2016

International Journal of  Hydrogen Energy
*Correspondence author


Optimized Expression and Purification for High-Activity Preparations of Algal [FeFe]-Hydrogenase

Yacoby I*, Tegler L, Pochkailov S, Zhang S*, King P*.  
Published on April 2012

*Correspondence authors

Photosynthetic electron partitioning between [FeFe]-hydrogenase and ferredoxin: NADP+-oxidoreductase (FNR) enzymes in vitro
Yacoby I*, Pochekailov S, Toporik H, Ghirardi ML, King PW*, Zhang S*. 
Published on May 2011
Proc Natl Acad Sci U S A 
*Correspondence authors
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